Found the following hamletworks.org entries referring to line 1281

View Commentary Note for 1280-1
1280-1 Ham. In the secret parts of Fortune, oh most true, | she is a strumpet,  

View Material Textual Note for 1280-1
1280-1 Ham. In the secret parts of Fortune, oh most true, | she is a strumpet,  

View Material Textual Note for 1281
1281 {What} <What's the> newes?2.2.236